Role of Epsilon Aminocaproic acid & Tranexamic Acid, vs Placebo in Reduction of mediastinal Bleeding following Open Heart Surgery

AUTHORS

Alireza Alizadeh Ghavidel 1 , ** , Naser Jalilifar 1 , *

1 Iran

Corresponding Authors:

How to Cite: Alizadeh Ghavidel A, Jalilifar N. Role of Epsilon Aminocaproic acid & Tranexamic Acid, vs Placebo in Reduction of mediastinal Bleeding following Open Heart Surgery, Multidiscip Cardio Annal. 2009 ; 2(4):e8724.

ARTICLE INFORMATION

Multidisciplinary Cardiovascular Annals: 2 (4); e8724
Published Online: July 08, 2009
Article Type: Research Article
Received: September 11, 2016
Accepted: July 08, 2009

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Abstract

Post-operative bleeding
is one of the Challenging issues in
cardiacsurgery. The Excessive bleeding
and need for transfusion of blood
products may increases the patients’
mortality and morbidity. Although use
of antifibrinolytics has long been the
issue of interest but recently according
to some reports of sudden death after
use of aprotinin has encountered great
limitations. So we decided to find an
alternative drug for aprotinin

Keywords

CABG, Mediastinal bleeding, Antifibrinolytic, Open Heart Surgery

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